| [ Instructions ] | [ Documentation ] | [ Save as default ] |
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part of the mcdcm project. free for non-commercial use. |
| [ Instructions ] | [ Documentation ] | [ Save as default ] |
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part of the mcdcm project. free for non-commercial use. |
| Instructions | ||
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Instructions: 1. Select the organ & field strength 2. Enter the TEs based on your protocol 3. Draw the ROIs on each slice 4. Enter the SIs corresponding to the TEs of each slice 5. Truncation is applied automatically. Use slider to adjust trunction manually Saving Defaults: 1. After selecting the organ & field strength, click on "Save as default" 2. After entering the TEs of your default protocol, click on "Save TEs" 3. These are saved as browser cookies. Please enable cookies for your browser. 4. The default organ & field strengh are loaded automatically next time 5. To load the previously saved TEs, click on "Load TEs" Program Info: 1. Tested on Chrome & IE 11 2. Fully coded in HTML5 / Javascript / CSS without external dependancies (including images) 3. For off-line use, just save as HTML file in your drive 4. Open-source and freely distributable for non-commercial use but credits & references must be maintained | ||
| Documentation | ||
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Equations for T2*-IC Conversion (1.5T): LIC = 31.94 x (T2*)-1.014 MIC = 45.0 x (T2*)-1.22 Corrections for 3T: Liver R2*3T = (R2*1.5T - 11) / 2 Myocardial R2*3T = (R2*1.5T - 15) / 1.88 Note : T2* = 1000 / R2* Technical Info: 1. Line is fitted using least-squares method 2. Automated truncation method is based on He et al (2013) for myocardial studies. (Note: due to absence of data, this method is applied to liver studies as well.) 3. Automatic truncation has the following logic: - if R2 is greater than 0.995 when all readings are measured (no truncation), accept results - if R2 is less than 0.995, truncate last reading and recalculate R2 - once R2 is greater than 0.995, continue truncating until the T2* is greater than 97.5% of the preceding T2*, then accept the truncated results - if T2* is greater than 20ms at any time, accept the truncated results - if none of the conditions are met, do not accept any results 4. If loaded from mcdcm viewer, SNR for each ROI is displayed on graph within parentheses. References: Carpenter, John-Paul, et al. "On myocardial siderosis and left ventricular dysfunction in hemochromatosis." J Cardiovasc Magn Reson 15.1 (2013): 24. Garbowski, Maciej W., et al. "Biopsy-based calibration of T2* magnetic resonance for estimation of liver iron concentration and comparison with R2 Ferriscan." Journal of cardiovascular magnetic resonance 16.1 (2014): 1. Hankins, Jane S., et al. "R2* magnetic resonance imaging of the liver in patients with iron overload." Blood 113.20 (2009): 4853-4855. He, Taigang, et al. "Automated truncation method for myocardial T2* measurement in thalassemia." Journal of Magnetic Resonance Imaging 37.2 (2013): 479-483. Storey, Pippa, et al. "R2* imaging of transfusional iron burden at 3T and comparison with 1.5 T." Journal of Magnetic Resonance Imaging 25.3 (2007): 540-547. Sourced from Excel Worksheet by: Juliano Lara Fernandes, University of Campinas - Brazil [jlaraf (at) fcm.unicamp.br] Ulrik Gram, Novartis Pharma AG - Switzerland [ulrik.gram (at) novartis.com] Dif-tor heh smusma \\//_ | ||